The folder you show in your screenshot is not the correct folder to install reshade.
If you're using an older version, some information might still apply, but that's not guaranteed. meant re install reshade, use 11 not 10 and when it prompts you asking if you want to download effects say yes then in game press left shift and F2 at the exact same time. Can cause framerate issues on lower end PCs. The ReShade overlay menu can be toggled in-game with Shift + F2 by default.
